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Bioptimus models are available three ways. The on-premise and SageMaker options share the same JSON API and are both supported by the Bioptimus SDK, so your inference code is portable between them.

AWS & SageMaker

Managed cloud endpoints from AWS Marketplace. Best for production and scale.

On-premise

Self-hosted container. Best for data residency and air-gapped environments.

Hugging Face

Direct H-Optimus weights for non-commercial academic research.

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Which should I choose?

For data residency and PHI considerations, see Security & compliance.