Skip to main content
For academic users, H-Optimus-1 weights are available directly on Hugging Face and can be loaded with timm — no server or AWS account required.
Non-commercial academic use only. H-Optimus-1 on Hugging Face is released under CC-BY-NC-ND 4.0. Commercial use, sale, or monetization (including models trained on its outputs) is prohibited without prior approval. For commercial use, deploy via AWS or on-premise, or contact Bioptimus.

1. Request access

Access is gated. On huggingface.co/bioptimus/H-optimus-1, accept the terms using your institutional email (it must match your Hugging Face account email to be approved).

2. Load the model and extract features

H-Optimus-1 expects 224×224 images extracted at 0.5 microns per pixel.
Mixed precision (autocast) is recommended for faster inference. The normalization constants above are specific to H-Optimus-1 — use them as shown.

When to use a different option

Need M-Optimus or commercial use?

M-Optimus and commercial licensing are available via AWS Marketplace.

Need whole-slide tooling?

The Bioptimus SDK handles tiling and tissue masking against a deployed server.